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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
17.27
Human Site:
S1136
Identified Species:
31.67
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S1136
E
E
S
V
L
K
N
S
D
V
E
P
T
A
N
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S1136
E
E
S
V
L
K
N
S
D
V
E
P
T
A
N
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S1136
E
E
S
V
L
K
N
S
D
V
E
P
T
A
N
Dog
Lupus familis
XP_543184
1286
146207
S1164
E
E
S
V
L
K
N
S
D
I
E
Q
T
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
S1081
E
E
S
V
L
K
S
S
D
V
E
Q
T
A
R
Rat
Rattus norvegicus
NP_001099552
648
74414
E540
K
L
R
G
E
N
K
E
A
G
G
T
K
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
A756
E
V
E
G
K
S
E
A
A
A
D
I
E
V
D
Chicken
Gallus gallus
XP_420401
1281
145243
N1157
E
E
S
T
L
K
A
N
V
I
K
C
M
T
N
Frog
Xenopus laevis
Q7ZZC8
944
104521
C836
P
S
F
Q
A
C
T
C
S
T
L
Q
E
E
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
C589
A
V
T
E
K
G
Q
C
F
T
F
G
S
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
D983
L
N
D
Q
H
D
D
D
D
L
V
I
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
E498
L
E
P
G
Q
N
R
E
G
A
I
M
K
A
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
D750
T
I
A
A
S
A
V
D
S
S
S
S
S
S
S
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
86.6
N.A.
80
0
N.A.
6.6
40
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
26.6
60
0
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
8
8
16
16
0
0
0
47
0
% A
% Cys:
0
0
0
0
0
8
0
16
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
8
8
16
47
0
8
0
8
8
16
% D
% Glu:
54
54
8
8
8
0
8
16
0
0
39
0
16
8
0
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
24
0
8
0
0
8
8
8
8
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
16
8
16
0
0
0
% I
% Lys:
8
0
0
0
16
47
8
0
0
0
8
0
16
0
0
% K
% Leu:
16
8
0
0
47
0
0
0
0
8
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% M
% Asn:
0
8
0
0
0
16
31
8
0
0
0
0
0
8
39
% N
% Pro:
8
0
8
0
0
0
0
0
0
0
0
24
0
0
0
% P
% Gln:
0
0
0
16
8
0
8
0
0
0
0
24
0
0
16
% Q
% Arg:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
47
0
8
8
8
39
16
8
8
8
16
8
8
% S
% Thr:
8
0
8
8
0
0
8
0
0
16
0
8
39
8
0
% T
% Val:
0
16
0
39
0
0
8
0
8
31
8
0
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _